Cerdelga: 25 years In The Making

Emily BurkeDiabetes, Drug Approvals, FDA, Genetics, Mechanism of Action, Orphan Disease, Orphan Drugs, Small Molecule Drugs, The WEEKLY

We have a new orphan drug on the market thanks to last week’s FDA approval of Cerdelga, a small-molecule therapeutic developed by Sanofi for treatment of Gaucher’s disease. This rare genetic disorder is thought to affect around 6,000 in the United States. Regular WEEKLY readers know we like to highlight new drug approvals. After all, there are only 25 to … Read More

A Chip Off The New Block

Emily BurkeBiotech Basics, Deoxyribonucleic Acid (DNA), Diagnostics, Genetics, The WEEKLY

PERSONAL GENOMICS TURNS HEADS IN BIOTECH 23andMe, the Silicon Valley based personal genomics company named for the 23 pairs of chromosomes in a normal human cell, is turning a few heads in the biotechnology industry lately. After a very public and still unresolved dust-up with the FDA’s decision to halt marketing of the company’s DNA-based personal “health reports,” 23andMe is … Read More

Cultivating Biologics From Plants?

Emily BurkeBiologics, Biomanufacturing, Biotech Basics, The WEEKLY

A FRESH LOOK AT TOBACCO AND BIOLOGICS Tobacco plants pioneering the production of monoclonal antibodies for an experimental Ebola treatment turned out to be quite the head scratcher for last Thursday’s WEEKLY readers. With tobacco’s reputation polluting our recent memories, let’s take a fresh look at tobacco and biologics. To date, no approved therapeutic protein has been produced in whole plants—ever! … Read More

Tiny Virus, Big Problem

Emily BurkeBiologics, Clinical Trials, Deoxyribonucleic Acid (DNA), Drug Development, Ebola, FDA, Ribonucleic Acid (RNA), The WEEKLY

YEARS IN THE MAKING, EBOLA BUBBLES TO THE SURFACE Bubbling under the surface for years like a volcano packing heat, Ebola erupts into a stark reality for the world health community. First appearring in 1976, Ebola is a classified “Category A” potential bioterrorism agent. With an incubation period of up to 21 days (early symptoms mimick the everyday flu), it is entirely possible that … Read More