Cracking The Circadian Code

Cracking The Circadian Code

Cracking the Circadian Code The most recent WEEKLY described the molecular basis of circadian rhythm, the internal 24-hour clock that governs many of our biological processes. Disrupting this cycle over the long term is linked to diseases including obesity, diabetes,...
PARP1 Inhibitor Takes On Pancreatic Cancer

PARP1 Inhibitor Takes On Pancreatic Cancer

PARP1 INHIBITORs PARP1 inhibitors are back in the headlines this week, as Astra Zeneca’s (Cambridge, England) and Merck’s (Kenilworth, New Jersey) Lynparza posted positive Phase III results from a trial with pancreatic cancer patients—a notoriously difficult...
An Epigenetic Liquid Biopsy

An Epigenetic Liquid Biopsy

A New Type of Liquid Biopsy Biopsy. It can bring to mind painful cutting, punching and poking. Thankfully, these important and potentially life-saving procedures have moved into the new millennium along with the rest of us. Liquid biopsies have become a hot area of...