The Science Behind the Headlines

Wading Deeper Into Biomanufacturing

Wading Deeper Into Biomanufacturing

Last week, we began our exploration of biomanufacturing--defining terms, introducing the different types of cells used in production, and explaining how manufacturers create cell banks to provide raw materials for the medicines some of us know and love. This week, we...

Breaking Down Drug Metabolism

Breaking Down Drug Metabolism

When popping a pill, how often do we think about what happens next—to the pill, or to our bodies? Maybe we assume the body welcomes any extra help to soothe our headache or control our blood pressure. This WEEKLY looks into the mystery of what comes after the swallow....

The ABCs Of mRNA Vaccines

The ABCs Of mRNA Vaccines

News of positive data from Moderna's (Cambridge, MA) Phase I trial of a COVID-19 vaccine has dominated this week's headlines. Their vaccine is an mRNA-based vaccine—an entirely new approach to not only vaccines but also to therapeutics.  mRNA-based drugs and vacines...

The Mechanics Of Melanoma

The Mechanics Of Melanoma

Despite restricted access to parks and beaches due to the COVID-19 pandemic, people everywhere continue to seek solace in outdoor activities, enjoying a walk through the neighborhood or a cold drink on a hot afternoon in a sunny backyard. Fresh air and sunlight are...

On A Tumor’s Turf

On A Tumor’s Turf

Solid tumors are generally considered more difficult to treat than blood cancers. For example, chimeric antigen receptor T-cell (CAR-T) therapy has been amazingly effective against blood cancers that failed to respond to other types of treatment, while inroads against...

COVID-19 Antivirals: Part Two

COVID-19 Antivirals: Part Two

Last week, we began our two-part series on COVID-19 antiviral drugs by reviewing the stages of the Sars-Cov-2 (the virus that causes COVID-19) lifecycle that might be prone to attack by these drugs, and explained how hydroxychloroquine (HCQ) works and discussed the...

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