Immune Checkpoint Inhibitors

Immune Checkpoint Inhibitors

A Killer(-T) Nobel Prize In Medicine On October 1, James Allison, now at the M.D. Anderson Cancer Center in Houston, and Tasuku Honjo, now at Kyoto University, won the 2018 Nobel Prize in Physiology or Medicine. The two scientists discovered the basis for today’s...
Immunotherapy Goes Viral

Immunotherapy Goes Viral

VIRUSES BLASTING CANCER Last week, Johnson & Johnson (New Brunswick, NJ ) announced that their biotech arm Janssen Labs (Rariton, NJ) is investing up to $1 billion dollars to acquire BeneVir, a small biotech based in Rockville, Maryland, which focuses on oncolytic...
CAR-NK: Natural Born Cancer-Killers

CAR-NK: Natural Born Cancer-Killers

Further Down the Cancer Treatment Road with CARs This past August, to much fanfare, the FDA approved the first chimeric antigen receptor (CAR) T-cell therapy for blood cancer. Called Kymriah (Novartis), it promises to revolutionize treatment by genetically altering a...
Eye Of The Cytokine Storm

Eye Of The Cytokine Storm

THE FLASH OF THE FIRST CAR-T Last week’s much anticipated FDA approval of the first chimeric antigen receptor T-cell (CAR-T) therapy for acute lymphocytic leukemia hails as the first gene therapy on the US  market. Classified as a “cell-based gene therapy,” Novartis’...