Putting The CAR-T Before The Horse

Putting The CAR-T Before The Horse

THE STORY BEHIND CAR-T The hottest cancer therapy in the pipeline — chimeric antigen receptor T-cells (CAR-T) — got a big boost last month when an FDA advisory panel unanimously recommended approval of the treatment for children and young adults with a severe form of...
Eye Of The Cytokine Storm

Eye Of The Cytokine Storm

Understanding CAR-T Safety Chimeric antigen receptor therapy (CAR-T) is our top technology pick of 2016, blazing trails in drug development with its innovative approach of using engineered immune cells to fight cancer. Despite its success in clinical trials, safety...
Neoantigen Cancer Vaccines

Neoantigen Cancer Vaccines

The Elusive Cancer Vaccine The promise of cancer vaccines have proven to be elusive. A new crop of biotechs are hoping to change that by taking advantage of the latest advances in genomics. Scientists are working overtime trying to develop cancer vaccines that train...
Next-Generation CAR-T

Next-Generation CAR-T

The Race Is On Our last WEEKLY—Hacking the Immune Response—unveiled the science behind CAR-T and TCR, two immunotherapies under the microscope of the mainstream press. The well-deserved media attention highlights the ability of these “living drugs” to recognize and...