Drug Discovery 201

Emily BurkeDrug Development, Drug Discovery, Drug Targets

WE WANNA NEW DRUG “One that won’t make me sick/ One that won’t make me crash my car/ and make me feel three feet thick…” Huey Lewis is singing about love, but he voices very human concerns when it comes to the medicines that heal bodies and minds. Last time, the Weekly explored how researchers identify drug targets—the molecules in … Read More

Drug Discovery 101

Emily BurkeDrug Development, Drug Discovery, Drug Targets

On the Road to New Medicines For most of the 20th century, we discovered new drugs by trial and error. Scientists investigated countless unrelated compounds in animals to see which improved disease symptoms. For instance, in the 1950s and 60s, British scientists at Boots Laboratories tested hundreds of unrelated chemicals on guinea pigs searching for an alternative to aspirin for … Read More