A Killer(-T) Nobel Prize In Medicine

Emily BurkeDrug Discovery, Edited by Sarah Van Tiem, Immunology, Immunotherapy

A Killer(-T) Nobel Prize In Medicine On October 1, James Allison, now at the M.D. Anderson Cancer Center in Houston, and Tasuku Honjo, now at Kyoto University, won the 2018 Nobel Prize in Physiology or Medicine. The two scientists discovered the basis for today’s hugely successful immune checkpoint inhibitor therapies. Let’s look at their discoveries and how they have revolutionized cancer treatment. Keeping The Immune System … Read More

Attack Of The Tregs!!

Emily BurkeDrug Discovery, Edited by Sarah Van Tiem, Immunology, Immunotherapy, Inflammation

Attack Of The Tregs!! No matter what it sounds like, this subset of helper T-cells aren’t invaders from another planet. Nope, Tregs, or regulatory T-cells, come from New Jersey (don’t say it!) and elsewhere.  They suppress the immune system. These newcomers to the drug discovery and development scene intrigue the men and women seeking new approaches to diabetes, cancer, and autoimmune disorders. … Read More