Breaking Bad With SCLC & NSCLC

Breaking Bad With SCLC & NSCLC

Breaking Down Lung Cancer  The hit TV series Breaking Bad features anti-hero Walter White, who starts out as a sympathetic character: a mild-mannered high school chemistry teacher with a nagging cough that turns out to be lung cancer. Money problems precipitated by...
The Multiple Myeloma Landscape

The Multiple Myeloma Landscape

BLOOD CANCER: MULTIPLE MYELOMA Plasma cells are the antibody-producing cells of our immune system which happen to play a critical role in our defense against infections. In multiple myeloma, plasma cells begin to grow and divide in an uncontrolled manner, forming a...
The PARP Race Is On

The PARP Race Is On

PARP1 INHIBITOR LINEUP PARP1 inhibitors are making a strong statement! Tesaro’s (Waltham, MA) just-approved Zejula has garnered predictions of blockbuster status. AstraZeneca’s (Cambridge, UK) Lynparza was the first PARP1 inhibitor to make it to market...
The Mechanics Of Melanoma

The Mechanics Of Melanoma

Spectrum Of Therapies Melanoma accounts for less than 1% of skin cancer cases yet causes the vast majority of skin cancer deaths. If detected early enough, melanoma is almost always curable. If not, its ability to metastasize makes it difficult to treat. Melanoma is...
Killing Cancer At Its Stem Cell Origin

Killing Cancer At Its Stem Cell Origin

Killing Cancer When it comes to killing cancer, eradicating every single cell is the goal. But did you know there are different kinds of cancer cells? One specific type, called cancer stem cells (CSC), is catching the eye of drug developers. Discovered more than a...
The Plight & Promise of p53

The Plight & Promise of p53

A Holy Grail? What if scientists could identify a mutated gene that accounts for more than half of all cancerous tumors? This gene would become a holy grail of cancer research. This gene exists, and it is called p53. The name p53 refers to its molecular...