Disrupting The Cycle

Disrupting The Cycle

Circadian Rhythms Govern More Than 24 Hours Of Your Day Overnight shift workers, students pulling an all-nighter to cram for a final exam, and business people rushing between time zones all share one thing in common: significant disruption to their circadian rhythm....
Attacking All Angles Of Alzheimer’s

Attacking All Angles Of Alzheimer’s

Alzheimer’s Pipeline Roundup Alzheimer’s disease ranks as one of the toughest nuts to crack within drug discovery and development. Current treatments merely manage symptoms, so finding a better solution becomes more and more urgent as the aging population grows....
Drugging The Undruggable

Drugging The Undruggable

Antagonists Fight A Good Fight Small molecule inhibitors, also known as antagonists in the industry, fight a good fight. In fact, many drugs on the market today work by inhibiting overactive, disease-associated proteins. Novartis’ (Basel, Switzerland) top...
Cancer Immunotherapy Goes Viral

Cancer Immunotherapy Goes Viral

Oncolytic Viruses Make Their Debut Does a virus engineered to harness the immune system to fight cancer sound like a clever idea? Amgen (Thousand Oaks, CA) certainly thinks so, because their talimogene laherparepvec (T-Vec) recently earned an FDA approval to fight...
A Big Pain

A Big Pain

The Science Behind Opioids President Obama’s recent plan to fight opioids highlights the dark side of a class of treatments serving a vital need. Opioid pain medications manage the severe short-term or chronic pain of millions of Americans. While these...