New Gene Therapy Drug Explained Novartis’ (Basel, Switzerland) Zolgensma grabbed headlines last week as it garnered the second FDA approval of a gene therapy treatment for an inherited disease. Designed to treat spinal muscular atrophy (SMA), Zolgensa is also set to...
Decoding The Gut-Brain Axis Earlier this week, a newly published study made headlines for showing a direct link between the gut microbiome and depression. For the past several years, scientists have suspected a link between bugs in the gut and neurological health....
What Can’t These Little Dudes Do? When last we met, we discussed the fundamentals of monoclonal (mAb) therapies and looked at two recent advances: antibody-drug conjugates and bispecific antibodies. This week continues our adventure in antibody innovation by...
The Science Behind the Deal Earlier this week, news of the $8.7 billion acquisition of gene therapy company AveXis (Bannockburn, IL) by Novartis (Basel, Switzerland) made big biotech headlines. AveXis’ lead candidate, AVXS-101, is now in Phase III clinical...
USING MEDICAL IMAGING TO INVESTIGATE DISEASE Medical imaging — using various modalities to take a snapshot of the body’s interior structure — has been around since 1895, with the discovery of X-rays by Wilhelm Roentgen. X-rays are a type of electromagnetic...
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