The Science Behind the Headlines

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Biotech for Non-Scientists

Pills, Peptides, & Proteins

Pills, Peptides, & Proteins

Promising Peptide Therapies   The front runners in the game of drug delivery include small molecule and large molecule drugs, but there is another class that lands right in between: peptides. Several companies, including Rhythm Pharmaceuticals (Boston, MA), Kalos...

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MICROBIOME ADVENTURES, PART 2

MICROBIOME ADVENTURES, PART 2

The most recent Biotech Primer WEEKLY looked at a particularly productive new area of medicine courtesy of our own tiny personal zoo: the microbiome. We considered how resetting a person’s microbiome with a fecal matter transplant (FMT) aka bacteriotherapy can heal such troubling conditions as antibiotic-resistant C. difficile infections and inflammatory bowel disease (IBD). Thankfully for the millions suffering from these health conditions, acceptance of FMTs is growing. Now the research community is turning its attention to the specific components behind the microbiome’s healing potential. Several biotech companies are already developing more precisely-defined therapeutics. This work will foster better quality control and more comfortable formulations. Who wouldn’t prefer swallowing a capsule to undergoing an enema or colonoscopy?

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Biomanufacturing: How Biologics Are Made

Biomanufacturing: How Biologics Are Made

Putting Nature to Work There’s more than one way to skin a cat. Or make medicine, for that matter. It all depends on the kind—tabby or calico? Small molecule or biologic? One key feature that distinguishes biologic drugs such as monoclonal antibodies from small...

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Medical Devices & Diagnostics

CRISPR’s GENOME DETECTIVES

CRISPR’s GENOME DETECTIVES

CRISPR’s GENOME DETECTIVES   Last week, we reviewed how CRISPR works and its potential to revolutionize genetic therapies. Here we look at how scientists have started using this technology to develop new diagnostics. Media attention has been focusing almost...

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